Why We Need People to Donate Their Brains
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The advances in scanning and imaging the brain
have been remarkable and you’ve all seen
the incredible images that one can obtain
and this is truly a miracle and been very
helpful in terms of many aspects of our understanding
of brain disease.
But unfortunately, these brain imaging devices
are limited in the resolution that they have
in terms of the size of an object that they
can actually distinguish.
When you compare that to looking at a brain
specimen, particularly under the microscope,
we can see things that are a thousand times
smaller than the best, let’s say MRI instrument,
which makes a huge difference.
We can see the nature of the disease on the
cellular level, which is really where you
need to go if you want to understand it, particularly
in a problem where we don’t have a basis
for understanding in terms of past knowledge,
because nobody had really actually collected
brains like this and studied them prior to
our work.