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Transcript for Jack Szostak interview: What was the most difficult step in the research that led to this discovery?
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| Time | Content |
|---|---|
| 00:02 → 00:09 |
I think the most difficult step, or process really, |
| 00:09 → 00:17 |
is that one tends to develop models as a way of guiding your thinking... |
| 00:17 → 00:23 |
...and it’s hard not to get too attached to a model that you’ve developed. |
| 00:24 → 00:29 |
Since we were working on recombination, and thinking about reactions of DNA ends, |
| 00:29 → 00:34 |
we had a lot of models that were based on those reactions. |
| 00:34 → 00:38 |
We kind of held on to those models, and it wasn’t until the data – |
| 00:38 → 00:44 |
– the DNA sequences, and the actual picture of what was going on – |
| 00:44 → 00:49 |
– forced us to say: all those models are wrong, we have to rethink things... |
| 00:49 → 00:55 |
...and come up with a new model that is consistent with the experiments. |
| 00:55 → 01:00 |
I think that’s a very common thing in science – and perhaps in life in general – |
| 01:00 → 01:04 |
that people get too attached to certain ideas. |
| 01:04 → 01:11 |
You have to be looking at reality and always adjust your ideas... |
| 01:11 → 01:15 |
... to be consistent with experiments. |