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Transcript for Tom Cech Interview - What is your favorite molecule?

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Time Content
00:01 → 00:04

What is my favorite molecule?

00:08 → 00:14

I think caffeine in the morning, because I need some strong coffee...

00:14 → 00:22

...but if you mean larger molecules, such as biological molecules, I would have to say that

00:22 → 00:28

...the telomerase RNA is now my favorite molecule to think about.

00:28 → 00:32

Telomerase is this enzyme that was discovered by...

00:32 → 00:39

...Elizabeth Blackburn and Carol Greider in California in the mid 1980s.

00:39 → 00:45

That is an unusual enzyme because it requires both an RNA component...

00:45 → 00:51

...and a protein component to replicate the ends of chromosomes.

00:51 → 00:57

And there is this wonderful interplay between the RNA and the protein,

00:57 → 01:04

which is not only important and medically important to cancer for example,

01:04 → 01:07

that we understand this particular machine,

01:07 → 01:13

but also it serves as a model for how RNA collaborates with protein...

01:13 → 01:16

...in biology more generally.