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Tom Cech Interview - What is your favorite molecule?
Duration:
1 minute and 17 seconds
Country:
Sweden
Language:
English
License:
CC - Attribution Non-commercial No Derivatives
Genre:
Documentary
Producer:
MoleClues TV
Director:
Per Thoren
Views:
163 (10 embedded)
Posted by:
locumele
on Sep 23, 2009
Nobel Prize winner Tom Cech interviewed for MoleClues.org
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Video Transcription
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What is my favorite molecule?
I think caffeine in the morning, because I need some strong coffee...
...but if you mean larger molecules, such as biological molecules, I would have to say that
...the telomerase RNA is now my favorite molecule to think about.
Telomerase is this enzyme that was discovered by...
...Elizabeth Blackburn and Carol Greider in California in the mid 1980s.
That is an unusual enzyme because it requires both an RNA component...
...and a protein component to replicate the ends of chromosomes.
And there is this wonderful interplay between the RNA and the protein,
which is not only important and medically important to cancer for example,
that we understand this particular machine,
but also it serves as a model for how RNA collaborates with protein...
...in biology more generally.
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